IMR Press / CEOG / Volume 45 / Issue 5 / DOI: 10.12891/ceog4589.2018

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Case Report
Mucinous cystadenoma of the ovary with stromal luteinization and hyperestrinism in a post-menopausal female
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1 Department of Pathology, University of Massachusetts Medical School, UMass Memorial Medical Center, Worcester, MA., USA
Clin. Exp. Obstet. Gynecol. 2018, 45(5), 787–788;
Published: 10 October 2018

Rare cases of virilization caused by ovarian tumors with functioning stroma have been reported, typically during pregnancy. The authors report a case of a post-menopausal 60-year-old woman who presented with breast tenderness and vaginal bleeding and was found to have an 18.4-cm adnexal mass by imaging. Cystectomy revealed a benign mucinous cystadenoma with stromal luteinization associated with elevated estradiol levels and features of hyperestrinism. Due to the high clinical suspicion of a malignancy, a total abdominal hysterectomy with bilateral salpingo-oophorectomy and appendectomy was performed. These hormonally induced changes must be recognized to avoid misinterpretation of a malignancy.
Mucinous cystadenoma
Stromal luteinization
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