IMR Press / CEOG / Volume 45 / Issue 4 / DOI: 10.12891/ceog4300.2018

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Case Report
Carcinoma of unknown primary site and ectopic pregnancy diagnosed at laparoscopic surgery: a rare coexistence
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1 Department of Obstetrics and Gynecology, Japanese Red Cross Fukuoka Hospital, Fukuoka, Japan
Clin. Exp. Obstet. Gynecol. 2018, 45(4), 626–628;
Published: 10 August 2018

The authors present a case of carcinoma of unknown primary site detected accidentally during laparoscopic surgery for ectopic pregnancy. A 36-year-old female patient (para 1, gravida 1) was referred to the present hospital with suspected ectopic pregnancy. Transvaginal ultrasound showed a right adnexal mass and echo-free space in the pelvic cavity. Her serum human chorionic gonadotropin level was 7,590 mIU/ml. The authors made a preoperative diagnosis of ectopic pregnancy and performed laparoscopic surgery. The ampulla of the right fallopian tube was enlarged and showed blood clotting. They noticed a white solid mass of size 1 cm on the peritoneum around the right pelvic ligament. Pathologic examination findings of the specimen were consistent with carcinoma. Immunohistochemical stains suggested high-grade neuroendocrine carcinoma. Routine metastatic workup could not reveal the original site. The final diagnosis was carcinoma of unknown primary site. The authors reviewed other case reports on neoplasms coexisting with ectopic pregnancy.
Ectopic pregnancy
Carcinoma of unknown primary site
Neuroendocrine tumor
Laparoscopic surgery
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