Despite rare prevalence of septic pelvic thrombophlebitis (SPT), high mortality and morbidity in untreated or delayed diagnosed cases are expected. Thus, early diagnosis and therapeutic management of disease is very vital. The present report describes a febrile case with strong suspicion to SPT that successfully responded to anticoagulant therapeutics. The patient was initially diagnosed with severe sepsis due to cesarean section and managed by antibiotic therapy. Because of persisting fever and no response to antibiotics, and with a strong suspicion of SPT, patient was treated with anticoagulant medication. Two days after beginning anticoagulant therapy, the nature of fever significantly changed to low grade and spiking. Four days later, she was completely afebrile. Therefore, SPT may imitate some common postoperative complications and thus should be considered as a serious post-cesarean event.