Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Purpose: The purpose of the study was to analyze the depth of embryo placement in the uterine cavity. Materials and Methods: This paper provides a review of published literature through searches of PubMed and MEDLINE from 2004 to 2015 to identify relevant studies that compared outcomes, mainly implantation, and pregnancy rates for women undergoing embryo transfer (ET) through the cervix following in vitro fertilization (IVF), or intracytoplasmic sperm injection (ICSI) cycles assessing the distance of where embryos were placed. A meta-analysis, three randomized controlled trials, and several retrospective and prospective studies were reviewed. Results: Most of the reviewed studies indicated that the embryo should be positioned at the tip of catheter in the middle area in regards of endometrial cavity around 10 to 20 mm away from fundus. Lower pregnancy rates have been also evaluated by the findings. Conclusion: It has been concluded that the site of embryo deposition usually affect the pregnancy rates and implantation.