IMR Press / CEOG / Volume 45 / Issue 2 / DOI: 10.12891/ceog3949.2018

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Case Report
Umbilical cord hemangioma associated with placental chorangiomatosis: a case report and literature review
Xin Liao1, 2Lian Xu1, 2Kaixuan Yang1, 2, *
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1 Department of Pathology, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University
2 Ministry of Education, West China Second University Hospital of Sichuan University, China
Clin. Exp. Obstet. Gynecol. 2018, 45(2), 303–306;
Published: 10 April 2018

A case of umbilical cord hemangioma associated with placental chorangiomatosis is reported. A premature male infant was delivered vaginally at 34 weeks of gestation. Congenital abnormality and visceral hemangioma were not detected after birth. The placenta did not exhibit any macroscopic abnormalities. In the middle of cord, an enlarged portion with 3 cm in length and 2.5 cm in diameter was identified. Microscopical examination revealed an umbilical cord hemangioma associated with segmental chorangiomatosis in the placenta. Among all the reported cases of umbilical cord hamangioma, only two cases were found associated with placental pathological changes, and neither of them was diagnosed with chorangiomatosis. As the first case reported umbilical cord hemangioma accompanied by placental chorangiomatosis, the pathological changes of umbilical cord hemangioma and associated placental changes are discussed in detail, and the relevant literature is reviewed in this report.
Umbilical cord
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