IMR Press / CEOG / Volume 45 / Issue 2 / DOI: 10.12891/ceog3804.2018

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 46 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Original Research
MD-TESE-ICSI using fresh sperm resulted in a lower rate of miscarriage compared with frozen-thawed sperm
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1 Department of Obstetrics and Gynecology, Asahikawa Medical University, Asahikawa, Japan
Clin. Exp. Obstet. Gynecol. 2018, 45(2), 229–230; https://doi.org/10.12891/ceog3804.2018
Published: 10 April 2018
Abstract

Purpose: Frozen-thawed embryo transfer achieves superior pregnancy and miscarriage rates compared with those achieved using fresh embryos, and there is no difference in fertilization rate using fresh versus frozen-thawed sperm collected by microdissection testicular sperm extraction (MD-TESE) when intracytoplasmic sperm injection (ICSI) is performed. However, there are few reports on the miscarriage rate using fresh versus frozen-thawed testicular sperm collected by MD-TESE. Materials and Methods: The present patient had been unable to conceive because of her husband’s azoospermia. Sperm was successfully collected via MD-TESE. ICSI using fresh or frozenthawed sperm was performed nine times. Results: Two fresh sperm ICSIs resulted in the delivery of two healthy babies. Seven frozen-thawed sperm ICSIs resulted in four pregnancies; however, three of these miscarried, and only one resulted in the delivery of a healthy baby. Conclusion: ICSI using fresh sperm decreased the rate of miscarriage compared with ICSI using frozen-thawed sperm in this patient.
Keywords
Miscarriage
Fresh sperm
Frozen-thawed sperm
ICSI
MD-TESE
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