IMR Press / CEOG / Volume 45 / Issue 1 / DOI: 10.12891/ceog3952.2018

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 46 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Case Report
Exacerbation of neurofibromatosis and adverse pregnancy outcome. A case report and review of the literature
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1 Department of Gynecology and Obstetrics, Venizeleio & Pananio General Hospital of Heraklion, Heraklion, Greece
2 Department of Ophthalmology, Konstantopouleio-Patission General Hospital of N.Ionia, Athens, Greece
3 Department of Surgery, St George's University Hospital NHS Foundation Trust Blackshaw Road, Tooting London, United Kingdom
Clin. Exp. Obstet. Gynecol. 2018, 45(1), 126–128; https://doi.org/10.12891/ceog3952.2018
Published: 10 February 2018
Abstract

Neurofibromatosis type 1 (NF-1) is a condition which has markedly variable clinical expressions. During pregnancy the manifestations of the disorder are exacerbated, and as a result, mild to severe maternal and fetal complications may appear. A case of neurofibromatosis affected by pregnancy is presented. The mother presented with high arterial blood pressure, renal insufficiency, and visual impairment. At the same time the baby was born with growth restriction and cerebellar haemorrhage. Altogether, NF1 is associated with increased maternal and fetal morbidity in pregnancy but not with increased maternal mortality.
Keywords
Neurofibromatosis
Obstetric complication
Visual impairment
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