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Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Original Research
Successful pregnancy following in vitro fertilization-embryo transfer in a woman with diminished oocyte
reserve despite a slow rising beta human chorionic gonadotropin level
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1
Cooper Medical School of Rowan University, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, NJ, USA
2
Cooper Institute for Reproductive and Hormonal Disorders, P.C., Mt. Laurel, NJ, USA
Clin. Exp. Obstet. Gynecol. 2017, 44(4), 509–510;
https://doi.org/10.12891/ceog3881.2017
Published: 10 August 2017
Abstract
Purpose: To present another rare case of a live pregnancy despite an inappropriate rising serum beta hCG level. Materials and Methods: A woman with diminished oocyte reserve had an in vitro fertilization (IVF) cycle, so the precise day of ovulation was known. Results: Despite an inappropriate doubling time for the serum beta-hCG level and a crown rump length sac size discrepancy (small sac), an apparently healthy fetus with no apparent anomalies has passed the second trimester. Conclusions: Despite the risk of ectopic pregnancies with slow rising hCG levels, and the generally very low chance of a successful viable pregnancy, one may need to not be too quick to terminate the pregnancy with methotrexate.
Keywords
Slow rising beta-hCG
Viable pregnancy
Small gestational sac
Diminished oocyte reserve
Methotrexate