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Original Research
A second case of successful conception in a natural cycle despite a maximum endometrial thickness in the follicular phase of four mm
J.H. Check1, 2, *
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1
Cooper Medical School of Rowan University, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, NJ, USA
2
Cooper Institute for Reproductive Hormonal Disorders, P.C., Marlton, NJ, USA
Clin. Exp. Obstet. Gynecol. 2017, 44(3), 341–342;
https://doi.org/10.12891/ceog3450.2017
Published: 10 June 2017
Abstract
Purpose: To report the second case of successful conception in a natural cycle despite a maximum endometrial thickness in the late follicular phase of four mm. Materials and Methods: A 31-year-old woman with short term infertility was evaluated for follicular endometrial maturation with pelvic sonography. Results: She was treated with progesterone in the luteal phase. Despite attaining a very good serum estradiol and having a longer follicular phase (with then more time of estrogen exposure to increase the endometrial thickness) she conceived in this cycle of investigation. Conclusions: Reporting a successful second case makes it less likely that the first case was a miracle. The odds are that there have been other pregnancies with four-mm endometrial thickness in natural cycles without follicle maturing drugs that have either not been reported, or more likely, not evaluated.
Keywords
Endometrial thickness
Thin endometrium
Natural cycle
Luteal phase support