IMR Press / CEOG / Volume 43 / Issue 6 / DOI: 10.12891/ceog3147.2016

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Original Research
Clinico-biochemical characteristics of 229 Portuguese infertile women with polycystic ovary syndrome: clinical relevance and relationship with fertility treatment results
Show Less
1 Department of Endocrinology, Portuguese Institute of Oncology, Lisbon
2 Department of Endocrinology, Hospital Santa Maria, CHLN, Lisbon
3 Department of Obstetrics and Gynecology, Reproductive Medicine Unit, Hospital Santa Maria, Lisbon (Portugal)
Clin. Exp. Obstet. Gynecol. 2016, 43(6), 812–817; https://doi.org/10.12891/ceog3147.2016
Published: 10 December 2016
Abstract

Purpose: Polycystic ovary syndrome (PCOS) affects 6-20% of reproductive-age women. The authors aimed to evaluate the characteristics of PCOS women and its relationship with fertility treatment outcomes. Materials and Methods: The authors reviewed records of PCOS women assisted at Hospital Santa Maria. Fertility treatment results were assessed as pregnancy rate, number of cycles, and miscarriage rate. Results: They identified 229 PCOS women, 179 (78.2%) had waist circumference > 80 cm, 72 (31.4%) had type 2 diabetes mellitus (T2DM) familial history and glucose abnormalities, hypertriglyceridemia and low cholesterol-HDL were detected in 23(10.1%), 15 (6.6%) and 103 (45.0%), respectively. Pregnancy was achieved in 164 women. The mean number of cycles to achieve pregnancy was 2.7 (±2.2). Statistical analysis identified factors associated with longer/higher number of treatments: primary infertility, T2DM familial history, hypertriglyceridemia, and low cholesterol-HDL. Waist circumference > 80 cm, older age, and increased LH level were associated with miscarriage. Conclusions: Primary infertility, T2DM familial history, hypertriglyceridemia, low cholesterol-HDL, older age, waist circumference > 80 cm, and high LH may confer poorer fertility treatment results.
Keywords
Polycystic ovary syndrome
Infertility
Oligomenorrhea
Clinical pregnancy
Spontaneous abortion
Share
Back to top