IMR Press / CEOG / Volume 43 / Issue 5 / DOI: 10.12891/ceog3294.2016

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Original Research
Percutaneous radiofrequency ablation for symptomatic uterine leiomyomas: a systematic review and meta-analysis
Show Less
1 Department of Radiology, Kangdong Seong-Sim Hospital, Hallym University College of Medicine, Seoul
2 Department of Preventive Medicine, College of Medicine, Korea University, Seoul (Korea)
3 Department of Literary Arts, Brown University, Rhode Island (USA)
Clin. Exp. Obstet. Gynecol. 2016, 43(5), 643–649; https://doi.org/10.12891/ceog3294.2016
Published: 10 October 2016
Abstract

Purpose: To evaluate the efficacy and safety of percutaneous radiofrequency ablation (RFA) in the treatment of uterine leiomyomas. Materials and Methods: Medline, Embase, and Cochrane databases were searched through August 2014 for all relevant studies on RFA for uterine leiomyomas. The efficacy and safety of RFA were assessed using the outcome measures of tumor volume, symptom severity score, health-related quality of life (HRQL) score, procedure-related complications, and reintervention. The authors calculated pooled event rates with 95% confidence intervals using random-effects model to assess the effects of RFA. Results: Eight observational studies were identified as eligible for inclusion in this meta-analysis and included 370 patients. All analyzed outcomes showed statistically significant improvements from baseline to final follow-up. Twenty-seven complications were identified and five of them qualified as major complications. Five patients required reintervention after RFA. Conclusions: Percutaneous RFA is an effective and safe treatment for patients with uterine leiomyomas.
Keywords
Uterus
Leiomyomas
Radiofrequency ablation
Meta-analysis
Share
Back to top