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Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Original Research
Clinical significance of group B streptococcus testing in late pregnancy
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1
Clinical Laboratory Department, Sichuan Academy of Medical Sciences & Sichuan Province People's Hospital, Chengdu
2
Luzhou Medical College, Luzhou (China)
Clin. Exp. Obstet. Gynecol. 2016, 43(5), 703–707;
https://doi.org/10.12891/ceog3123.2016
Published: 10 October 2016
Abstract
Purpose: This study aimed to detect the maternal group B streptococcus (GBS) by real-time PCR method, aiming to understand its germ-carrying situations and clinical significance. Materials and Methods: The secretions of one-third inferior segment of maternal vagina of 1,540 pregnant and postnatal women were collected for GBS detection by real-time PCR method, and the impacts of positive results on the fetus were observed. Results: The detection rate of GBS was 5.6% (86/1540); the premature birth rate of GBS-positive pregnant women was 29.1% (25/86), the miscarriage rate was 19.8% (17/86), the premature rupture rate was 26.7% (23/86), and the fetal distress rate was 24.4% (21/86). Conclusions: The GBS germ-carriers showed increased rates of premature birth, miscarriage, premature rupture, and fetal distress, thus forming adverse effects towards the maternal and infant outcomes.
Keywords
Group B streptococcus (GBS)
Real-time fluorescence PCR
Impacts on mother and child