IMR Press / CEOG / Volume 43 / Issue 4 / DOI: 10.12891/ceog2095.2016

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 46 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Original Research
The relationship between uterine prolapse and premalignant endometrial pathology
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1 Department of Obstetrics and Gynecology, Sifa University School of Medicine, İzmir
2 Department of Obstetrics and Gynecology, Celal Bayar University School of Medicine, Manisa
3 Department of Obstetrics and Gynecology, Eagean Maternity and Women’s Health Training Hospital, İzmir (Turkey)
Clin. Exp. Obstet. Gynecol. 2016, 43(4), 500–503;
Published: 10 August 2016

Objective: The aim of this study was to stress the importance of performing a thorough uterine assessment before selecting an organsparing surgery in patients presenting with uterine prolapse and no other complaints. Materials and Methods: This study included a total of 111 participants who presented with pelvic organ prolapse and underwent hysterectomy for grades 3-4 uterine prolapse. The posthysterectomy histopathology results were classified as benign (atrophic endometrium, proliferative or secretory endometrium) or pathologic (endometrial hyperplasia, endometrial polyp, adenomyosis, myoma uteri, and endometrium carcinoma). Results: Of the 111 patients enrolled in this study, 23 (20.2%) had endometrial hyperplasia, eight (7.2%) had endometrial polyps, 30 (27%) had uterine fibroids, and 20 (18%) had adenomyosis. Conclusion: There may be premalignant lesions of the endometrium in both premenopausal and postmenopausal women presenting with uterine prolapse and no other symptoms. A chronic inflammatory process resulting from the extra-vaginal location of the uterus may play a role in the development of these lesions. Further studies are needed on this subject.
Uterine prolapse
Endometrial hyperplasia
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