IMR Press / CEOG / Volume 43 / Issue 3 / DOI: 10.12891/ceog3124.2016

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 46 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Original Research
N terminal-pro brain natriuretic peptide in fetal umbilical cord meconium-stained amniotic fluid: a prospective case control study
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1 Obstetrics and Gynecology Department, Zekai Tahir Burak Women's Health Education and Research Hospital, Ankara
2 Department of Internal Medicine, Ankara Education and Research Hospital, Ankara
3 Department of Biochemistry, Fatih University School of Medicine, Ankara (Turkey)
Clin. Exp. Obstet. Gynecol. 2016, 43(3), 370–373;
Published: 10 June 2016

Purpose of investigation: To evaluate the value of N terminal-pro brain natriuretic peptide (NTpBNP) levels in fetuses with meconium-stained amniotic fluid (MSAF). Materials and Methods: In this case control study, of 36 fetuses, 19 had MSAF and 17 had normal, as controls. The blood samples were taken from the fetal umbilical cord just after birth to measure NTpBNP levels. Results: Mean NTpBNP values were 1.01 ± 0.49 ng/ml in the patient group and 1.70 ± 0.93 ng/ml in the control group. The difference between the groups was statistically significant (p = 0.01) and power was 78% at 95% confidence interval. Conclusion: Serum NTpBNP levels were decreased in the study group. The result suggests that NTpBNP may be a valuable marker for fetuses with MSAF.
Fetal acidosis
Fetal hypoxia
Meconium-stained amniotic fluid
N-terminal-pro brain natriuretic peptide
Umbilical cord
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