IMR Press / CEOG / Volume 43 / Issue 3 / DOI: 10.12891/ceog2096.2016

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 46 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Original Research
The incidence and risk factors of venous thromboembolism following elective gynecological surgeries without systemic thromboprophylaxis - an observational cohort study in a Chinese tertiary hospital
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1 Department of Obstetrics and Gynecology, Beijing Chao-yang Hospital affiliated to Capital Medical University, Beijing (China)
Clin. Exp. Obstet. Gynecol. 2016, 43(3), 365–369; https://doi.org/10.12891/ceog2096.2016
Published: 10 June 2016
Abstract

Purpose of investigation: To investigate the incidence and risk factors of venous thromboembolism (VTE) after gynecological surgery without systemic thromboprophylaxis. Materials and Methods: Consecutive adult Chinese medical patients not receiving pharmacological or systemic mechanical prophylaxis for VTE before elective gynecological surgery. An observational cohort study of 620 patients in a gynecological department in a Chinese tertiary hospital. Results: Lower extremity deep venous thrombosis was detected by ultrasound examination in 57 (9.19%) of the patients, 39 had computed tomography pulmonary angiography (CTPA) evaluation after being diagnosed with lower extremity deep venous thrombosis (LEDVT), and the diagnosis was confirmed in 18 subjects, resulting in a pulmonary embolism (PE) incidence of 46.2% among the 39 patients, and 13 (72.2%) were asymptomatic and without significant clinical features. Conclusions: In the absence of pharmacological or systemic mechanical prophylaxis, gynecological surgeries carried a significant risk for VTE in the Chinese study population. As clinical features are not able to reliably exclude the presence of PE, early routine prophylaxis is warranted based on risk factors in postoperative gynecological patients and should strongly be considered.
Keywords
Venous thromboembolism (VTE)
Pulmonary embolism (PE)
Gynecological surgery
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