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Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Original Research
The effect of clomiphene citrate vs. letrozole on post-coital tests
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1
Cooper Medical School of Rowan University, Department of Obstetrics and Gynecology
1
Division of Reproductive Endocrinology & Infertility, Camden, NJ
2
Cooper Institute for Reproductive Hormonal Disorders, P.C., Mt. Laurel, NJ (USA)
Clin. Exp. Obstet. Gynecol. 2016, 43(2), 184–185;
https://doi.org/10.12891/ceog3288.2016
Published: 10 April 2016
Abstract
Purpose: To determine if letrozole is less likely to create a hostile cervical mucus than clomiphene citrate. Materials and Methods: ost-coital testing compared at time of peak follicular maturation in women attaining mature follicles in first or second cycle of these wo drugs. The study was randomized. Intercourse occurred at least 8-16 hours before. Results: Poor post-coital tests were found in twice he frequency in letrozole cycles than clomiphene citrate cycles. Conclusions: Despite its shorter half-life, letrozole seems to be as least s likely, if not more, to adversely affect cervical mucus.
Keywords
Post-coital test
Cervical mucus
Clomiphene citate
Letrozole