IMR Press / CEOG / Volume 43 / Issue 2 / DOI: 10.12891/ceog2054.2016

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Case Report
Ganglioneuroblastoma during pregnancy – A rare case report
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1 Obstetrics and Gynecology, Transilvania University of Brasov, Brasov (Romania)
1 Hatieganu, Faculty of Dental Medicine, Maxillo-Facial Surgery and Radiology Department, Cluj-Napoca (Romania)
2 Obstetrics and Gynecology, Hippokratio General Hospital, Aristotle Univesity of Thessaloniki, Thessaloniki (Greece)
3 Transilvania University of Brasov, Brasov (Romania)
4 “Dr. I. A. Sbarcea” Clinical Obstetrics and Gynaecology Hospital, Brasov (Romania)
5 Hippokratio General Hospital, Aristotle Univesity of Thessaloniki, Thessaloniki (Greece)
6 University of Medicine and Pharmacy Iuliu
Clin. Exp. Obstet. Gynecol. 2016, 43(2), 265–267; https://doi.org/10.12891/ceog2054.2016
Published: 10 April 2016
Abstract

Purpose: To report a rare case of ganglioneuroblastoma encountered rarely in adults, especially during pregnancy. Materials and Methods: The authors present a case of ganglioneuroblastoma relapse during the third trimester of pregnancy in a patient previously treated for ganglioneuroblastoma who had a eight-year disease-free interval. Late manifestation of neurological symptoms (vestibular syndrome, nystagmus, slightly right motor deficit) was perhaps influenced by the hormonal pregnancy effects. In this case the option was for caesarean section under general anesthesia at 36 weeks. Results: Based on MRI result, the neurosurgical consultation stated the need of postpartum brain tumor excision. Recovery of the mother was complication-free with persistent, constant postoperative neurological symptoms. It resulted in a healthy newborn, not requiring special follow-up. Conclusions: Pregnancy and brain tumor have mutual negative effect on the patient. Therapeutic management in this case was a medical dilemma regarding mode setting and timing of delivery, taking into account the maternal-fetal risk-benefit.
Keywords
Ganglioneuroblastoma
Pregnancy
MRI
Caesarian section
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