IMR Press / CEOG / Volume 42 / Issue 5 / DOI: 10.12891/ceog1981.2015

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 46 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Original Research
The effectiveness of misoprostol or dinoprostone in neonatal outcome after labour induction in post-term nulliparas
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1 General Hospital Kavala, Kavala
2 Democritus University of Thrace, Department of Obstetrics and Gynecology, Alexandroupolis (Greece)
Clin. Exp. Obstet. Gynecol. 2015, 42(5), 649–652; https://doi.org/10.12891/ceog1981.2015
Published: 10 October 2015
Abstract

Objective: The object of this study was to investigate the efficacy of vaginal administration of misoprostol versus dinoprostone in neonatal outcome. Materials and Methods: The first Group A included 77 pregnant women, who requested pregnancy termination one week after labour term and received vaginally misoprostol 50 μg, while the other 69 pregnant women in Group B were vaginally administrated three mg dinoprostone. According to the authors’ protocol this procedure was repeated after six hours for a maximum of two times. Results: The labour duration was longer in Group B (p = 0.000), while the APGAR score was better in Group A (p = 0.015). In Group A the labour modus was as follows: 86.9% normal vaginal labour, 3.8% vacuum extraction, and 9.3% cesarean section, while in Group B it was 82.83% normal vaginal labour, 3.07% vacuum extraction, and 14.1% cesarean section. Conclusion: Misoprostol has advantages according to neonatal outcome compared to administration of dinoprostone.
Keywords
Misoprostol
Dinoprostone
Neonatal outcome
Post-term induction
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