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Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Original Research
Detection of a microgonadotropinoma by magnetic resonance imaging performed because of excellent response to controlled ovarian hyperstimulation despite elevated day 3 FSH
J.H. Check1,*, W. Dowland2
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1
Cooper Medical School of Rowan University, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, NJ
2
Mercy Health Partners, Department of Obstetrics and Gynecology, Muskegon, MI (USA)
Clin. Exp. Obstet. Gynecol. 2015, 42(3), 279–281;
https://doi.org/10.12891/ceog1813.2015
Published: 10 June 2015
Abstract
Purpose: To determine if a better response than anticipated to controlled ovarian stimulation in a woman assumed to have diminished oocyte reserve based on an increased day 3 serum follicle stimulating hormone (FSH) level, could be related to a gonadotropinoma. Materials and Methods: Magnetic resonance imaging (MRI) with and without gadolinium contrast was used in a woman who made 21 mature oocytes despite a history of day 3 serum FSH as high as 20 mIU/mL. Results: A pituitary microgonadotropinoma was detected. Conclusions: The presence of a better response than anticipated to controlled ovarian hyperstimulation (COH) with exogenous gonadotropins despite an increase in day 3 serum FSH should prompt a search for a possible gonadotropinoma.
Keywords
Gonadotropinoma
Controlled ovarian hyperstimulation
Follicle stimulating hormone
Early follicular phase