IMR Press / CEOG / Volume 42 / Issue 1 / DOI: 10.12891/ceog1949.2015

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 46 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Original Research
Troponin I and D-Dimer levels in preeclampsia and eclampsia: prospective study
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1 Kafkas University School of Medicine, Department of Obstetrics and Gynecology, Kars
2 Taksim Education and Research Hospital, Department of Obstetrics and Gynecology, Istanbul
3 Park Hospital IVF Center, Malatya (Turkey)
Clin. Exp. Obstet. Gynecol. 2015, 42(1), 26–31; https://doi.org/10.12891/ceog1949.2015
Published: 10 February 2015
Abstract
Objective: The aim of this study was to evaluate serum cardiac troponin I and D-Dimer (D-Di) levels in preeclampsia (PE), eclampsia(E), and normotensive healthy pregnant women in third trimester in order to define their diagnostic value. Materials and Methods:The study group consisted of 42 preeclamptic patients and 16 eclamptic patient; 108 healthy normotensive pregnant women in thirdtrimester who were chosen from outpatients clinic and examined regularly used as a control group. Serum cardiac troponin I and D-Dilevels were measured using an immunoassay. Results: The average levels of troponin I were 0.0134 ± 0.0091, 0.017 ± 0.0085, 0.180 ±0.136 in control group, preeclamptic, and eclamptic patients, respectively. The levels of troponin in eclamptic patients were statisticallyhigher than the normotensive and preeclamptic group (p = 0.016, p = 0.014). There were no differences in terms of troponin I level betweenpreeclamptic group and normotensive pregnant women in third trimester (p = 0.089). The average D-Di levels were 634 ± 228ng/ml, 1426 ± 430 ng/ml, 2067± 580 ng/ml in control group, preeclamptic, and eclamptic patients, respectively. The levels of D-Di inpreeclamptic and eclamptic patients were found significantly higher than the control groups (p = 0.034, p = 0.020). Conclusion: Serumtroponin I levels increased in eclamptic patient because of myocardial damage. An increased level of troponin was not detected inpreeclamptic patients. However; D-Di level increased in preeclamptic and eclamptic patients.
Keywords
Preeclampsia
Eclampsia
D- Dimer
Troponin I
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