IMR Press / CEOG / Volume 41 / Issue 6 / DOI: 10.12891/ceog17572014

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Original Research
Relation of red cell distribution width to the presence and severity of endometriosis
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1 Mustafa Kemal University Medical School, Department of Obstetrics and Gynecology, Hatay
2 Zekai Tahir Burak Women’s Health Education and Research Hospital, Ankara (Turkey)
Clin. Exp. Obstet. Gynecol. 2014, 41(6), 713–716; https://doi.org/10.12891/ceog17572014
Published: 10 December 2014
Abstract

Aim: Although the exact pathogenesis of endometriosis is not known, it is proposed to be a chronic inflammatory disease. The association between red cell distribution width (RDW) and inflammation is well established. Therefore, in the present study, the authors aimed to investigate the association between presence and severity of endometriosis and RDW. Materials and Methods: Fifty endometriosis patients and 48 controls were included in the study. The endometriosis group was categorized in two subgroups as mild-to-moderate (n=35) and moderate-to-severe disease (n=15). CA-125 and RDW values of all participants were measured. Results: Both RDW (17.7 ± 2.2 vs 14.9 ± 1.5, p < 0.001) and CA-125 (50.6 ± 35.1 vs 27.9 ± 4.8) levels were significantly higher in the endometriosis patients when compared to the control group. Moreover the authors found a significant positive correlation between RDW and CA-125 levels (r: 0.495, p < 0.001). Conclusion: The present study results demonstrated that RDW levels were significantly increased in endometriosis patients and associated with the severity of endometriosis.
Keywords
Red cell distribution width
Endometriosis
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