IMR Press / CEOG / Volume 41 / Issue 2 / DOI: 10.12891/ceog16922014

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 46 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Case Report
Complete eradication of chronic long standing eczema and keratosis pilaris following treatment with dextroamphetamine sulfate
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1 Cooper Medical School of Rowan University, Department of Obstetrics and Gynecology
1 Division of Reproductive Endocrinology & Infertility, Camden, NJ
2 Cooper Institute for Rowan Reproductive Hormonal Disorders, P.C., Marlton, NJ
3 Kaiser Permanente Los Angeles Medical Center, Department of Dermatology, Los Angeles, (USA)
Clin. Exp. Obstet. Gynecol. 2014, 41(2), 202–204;
Published: 10 April 2014

Purpose: To present two other dermatologic conditions related to a disorder of sympathetic nervous system hypofunction common in women that respond to treatment with dextroamphetamine sulfate – chronic eczema and keratosis pilaris. Materials and Methods: Case 1 was a patient with chronic eczema of 30 years duration was started on treatment for other conditions related to the sympathetic neural hyperalgesia edema syndrome, i.e., migraine headaches and chronic fatigue syndrome. Case 2 who also had chronic eczema also had a skin condition frequently associated with eczema – keratosis pilaris and he was started on dextroamphetamine sulfate for chronic fatigue syndrome. Results: Not only did the headaches and chronic fatigue syndrome in both patients markedly improve following sympathomimetic amine therapy but so did the eczema and keratosis pilaris. Conclusions: Eczema and keratosis pilaris are two more chronic dermatologic conditions besides chronic urticaria and prurigo nodularis that respond extremely well to treatment with dextroamphetamine sulfate. Case 2 shows this condition is not restricted to females.
Chronic eczema
Keratosis pilaris
Sympathomimetic amines
Sympathetic nervous system hypofunction
Sympathetic neural hyperalgesia edema syndrome
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