IMR Press / CEOG / Volume 41 / Issue 2 / DOI: 10.12891/ceog16622014

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 46 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Original Research
Application of two-dimensional echocardiography combined with enhanced flow in diagnosing fetal heart malformation
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1 Department of Ultrasound in Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijing
2 Department of Ultrasound in Medicine, Henan Provincial Hospital, Zhengzhou (China)
Clin. Exp. Obstet. Gynecol. 2014, 41(2), 195–201; https://doi.org/10.12891/ceog16622014
Published: 10 April 2014
Abstract

Objective: The current study aims to evaluate the diagnostic accuracy of two-dimensional echocardiography combined with enhanced flow (e-flow) imaging for fetal heart malformation. Materials and Methods: A total of 1,639 pregnant women were enrolled. They were examined using fetal echocardiography combined e-flow. The obtained results were compared with those by postnatal examination or post-induction autopsy. Results: Complete data were obtained from 1,286 out of the 1,639 fetuses (78.46%). Two-dimensional echocardiography combined with e-flow imaging had sensitivity, specificity, a misdiagnosis rate, and a missed diagnosis rate of 98.0%, 99.3%, 2.0%, and 0.7%, respectively. It has a consistency evaluation Kappa value of 0.970 (p = 0.000). Conclusion: Two-dimensional echocardiography combined with e-flow is an accurate and reliable diagnostic method for fetal heart malformation. It has high sensitivity and specificity.
Keywords
Fetal echocardiography
Congenital heart disease
Enhanced flow imaging
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