IMR Press / CEOG / Volume 41 / Issue 2 / DOI: 10.12891/ceog15892014

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 46 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Original Research
Establishment of reference range for thyroid hormones in normal pregnant women in China’s coastal area
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1 Department of Nuclear Medicine, Second Affiliated Hospital of Fujian Medical University, Quanzhou
2 Department of Laboratory, First Hospital of Quanzhou Affiliated to Fujian Medical University, Quanzhou
3 Library of Second Affiliated Hospital of Fujian Medical University, Quanzhou
4 Department of Obstetrics and Gynaecology, Second Affiliated Hospital of Fujian Medical University, Quanzhou
5 Second Department of surgery, Shishi (Overseas Chinese) Hospital, Quanzhou (China)
Clin. Exp. Obstet. Gynecol. 2014, 41(2), 135–140; https://doi.org/10.12891/ceog15892014
Published: 10 April 2014
Abstract

Purpose: The current study aims to establish reference ranges for thyroid hormones in normal pregnant women during their pregnancy period. Materials and Methods: A one-time cross-sectional survey was conducted on 490 normal pregnant women and 51 nonpregnant women (control). The serum thyroid stimulating hormone (TSH), free triiodothyronine (FT3), and free tetraiodothyronine (FT4) levels were measured. Results: The serum FT3 and FT4 levels in pregnant women decreased gradually from the first to the last three months of pregnancy (p < 0.01). The serum TSH level increased gradually during the whole pregnancy (p < 0.01), and was significantly lower than the control (p < 0.01) in the first three months. However, in the middle and last three months of pregnancy, TSH was higher than the control (p < 0.01). Conclusions: The thyroid hormone levels in normal pregnant women are different from those in non-pregnant women; significant differences exist among the three stages of pregnancy.
Keywords
Pregnancy
Stage of pregnancy
Thyroid hormone
Reference range
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