IMR Press / CEOG / Volume 41 / Issue 1 / DOI: 10.12891/ceog16092014

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 46 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Original Research
A study comparing three different laser-assisted hatching techniques
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1 Reproductive Center, Shenzhen Police Hospital, Shenzhen
2 Department of Obstetrics and Gynecology, Guangxi Medical University, Nanning (China)
Clin. Exp. Obstet. Gynecol. 2014, 41(1), 37–40; https://doi.org/10.12891/ceog16092014
Published: 10 February 2014
Abstract

Purpose of investigation: Laser-assisted hatching (LAH) is recognized as a useful technology to improve clinical pregnancy rates and implantation rates. This study reports the differences between a new LAH method and two conventional LAH techniques. Materials and Methods: The authors studied 151 patients with repeated implantation failure, who were divided into three groups. Results: In group 1, the zona pellucida (ZP) was opened using LAH (n = 52). In group 2, laser-assisted thinning was performed to dissolve the outer layer of the ZP (n = 49). In group 3, laser-assisted thinning was performed to dissolve the inner layer of the ZP (n = 50). The clinical pregnancy rates and implantation rates among the groups were compared. The results demonstrate that there are significant differences in the clinical pregnancy rates and implantation rates between group 3 and the other two groups. Conclusion: Performing laser-assisted thinning to dissolve the inner layer of the ZP markedly increases the pregnancy rates and implantation rates of patients with repeated implantation failure.
Keywords
Laser-assisted hatching
Recurrent implantation failure
Clinical pregnancy rates
Implantation rates
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