IMR Press / CEOG / Volume 40 / Issue 2 / pii/1630388173891-1608157671

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Original Research
A comparison of clinical pregnancy rates and multiple gestation rates with 2 vs 3 embryos transferred with pairs matched for embryo quality
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1 Albert Einstein Hospital, Department of Obstetrics and Gynecology, Philadelphia, PA
2 Cooper Medical School of Rowan University, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, NJ
3 The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, Cooper Hospital/University Medical Center, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, NJ (USA)
Clin. Exp. Obstet. Gynecol. 2013, 40(2), 196–197;
Published: 10 June 2013
Abstract

Purpose: To determine the impact of embryo quality on multiple birth rates. Materials and Methods: A retrospective review of in vitro fertilization-embryo transfer (IVF-ET) cycles over ten years was performed. The data was stratified by number of embryos transferred (two vs three) and by percentage of embryos with < 6 vs ≥ 6 blastomeres. Results: Pregnancy rates (PRs) increase with the greater number of embryos with a higher blastomere count. However transferring more embryos with less blastomeres does not lower the risk of multiple births. Conclusions: Couples should consult the table, e.g. presented here, so they can make their best choice of how many embryos to transfer considering the importance of a higher pregnancy rate vs the risk of the complication of multiple births.
Keywords
Blastomere number
Embryo quality
Multiple birth
In vitro fertilization-embryo transfer
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