IMR Press / CEOG / Volume 40 / Issue 1 / pii/1630388044276-626426720

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 46 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Origianal Research
Comparison of HbA1c levels in obese and non-obese polycystic ovarian patients
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1 Department of Obstetrics and Gynecology, Bilecik Central Hospital, Bilecik
2 Department of Obstetrics and Gynecology
3 Department of Biochemistry, Kecioren Education and Research Hospital, Ankara
4 Department of Biostatistic, Hacettepe University, Ankara (Turkey)
Clin. Exp. Obstet. Gynecol. 2013, 40(1), 148–150;
Published: 10 March 2013
Abstract

Aim: To compare obese and non-obese polycystic ovary syndrome (PCOS) patients with respect to lipid profile, hormone profiles, and hemoglobin A1c (HbA1c) values indicating chronic hyperglicemia. Materials and Methods: Thirty PCOS patients with a body mass index (BMI) > 25 and 35 non-obese PCOS patients with BMI < 25 were compared with regard to basal luteinizing hormone (LH), follicle-stimulating hormone (FSH), prolactin (PRL), estradiol (E2), fasting blood sugar (FBS), low-density lipoprotein (LDL), high-density lipoprotein (HDL), total cholesterol (TCOL), triglyceride (TG), and HbA1c values. Results: HDL value (p = 0.005) was significantly higher in non-obese group while TG (p = 0.001) was higher in the obese group. No significant difference was found between other values. Conclusion: Lipid metabolism impairment seems to be more marked in obese PCOS patients. Moreover, it is obvious that insulin resistance is higher in obese group. The absent difference between obese and non-obese groups in terms of HbA1c values suggests that insulin resistance occurring in the obese group may also be important in the non-obese group. In this context, cardiovascular risks may increase in non-obese PCOS patients.
Keywords
Polycystic ovary syndrome
Obese
HbA1c
Lipid metabolism
Insulin resistance
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