IMR Press / CEOG / Volume 39 / Issue 3 / pii/1630480824546-1885838583

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Editorial
Understanding the physiology of folliculogenesis serves as the foundation for perfecting diagnosis and treatment of ovulatory defects
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1 The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden Cooper Hospital/University Medical Center, Department of Obstetrics and Gynecology Division of Reproductive Endocrinology & Infertility, Camden, NJ (USA)
Clin. Exp. Obstet. Gynecol. 2012, 39(3), 273–279;
Published: 10 September 2012
Abstract

Purpose: To discuss updated physiologic information concerning the mechanism of folliculogenesis. Methods: Physiology studies involving the growth of primordial follicular growth and pre-antral growth to the development of the corpus luteum are discussed. Results: Benefits in aiding fertility potential and pitfalls of these drugs in preventing embryo implantation are discussed with reference to the physiologic processes required for folliculogenesis. Conclusions: Knowledge of the physiology of folliculogenesis can provide further understanding of luteal function when taking follicle maturing drugs and complications, as premature luteinization and the luteinized unruptured follicle syndrome. Also, this knowledge helps to create novel therapies to prevent ovarian hyperstimulation syndrome, endometrial receptivity defects, and treating women with diminished oocyte reserve.
Keywords
Antral follicle
Pre-antral follicles
Luteinizing hormone
Follicle stimulating hormone
Ovarian oocyte reserve
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