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Original Research
Successful pregnancy following a single fresh embryotransfer in a 45-year-old woman whose early follicular phase serum follicle stimulating hormone was 29 mIU/mL
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The University of Medicine and Dentistry of New Jersey,Robert Wood Johnson Medical School at Camden, Cooper Hospital/University Medical Center, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertiliry, Camden, NJ (USA)
Clin. Exp. Obstet. Gynecol. 2011, 38(4), 335–337;
Published: 10 December 2011
Abstract
Purpose: To determine if a successful pregnancy is possible following in vitro fertilization embryo transfer (IVF-ET) in a woman of advanced reproductive age with diminished egg reserve. Methods: In vitro fertilization-embryo transfer with intracytoplasmic sperm injection (ICSI) was performed for a 45-year-old woman with a peak serum follicle stimulating hormone(FSH) level of 29 mlU/mland a history of failing to conceive in five previous TVF-ET cycles at a younger age. A minimal FSH stimulation protocol was used. Results: A fresh transfer of a 7-cell embryo was performed on day 3. A successful pregnancy and delivery ensued. Conclusion: This case report establishes a precedent that a successful pregnancy following IVF-ET is possible in a woman whose serum FSH is > 15mIU/ml, and is age 45. Of course, there is no implication that accomplishing this again in another woman with similar circumstances would be likely.
Keywords
Advanced reproductive age
In vitro fertilization
Diminished egg reserve