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Evidence that migraine headaches in women may be related to a common defect in the sympathetic nervous system as evidenced by marked improvement following treatment with sympathomimetic amines
1 The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, Cooper Hospital/University Medical Center, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Inferility, Camden, NJ (USA)
Clin. Exp. Obstet. Gynecol. 2011, 38(2), 180–181;
Published: 10 June 2011
Purpose: To describe a novel therapy for women with intractable migraine headaches. Methods: Dextroamphetamine sulfate was prescribed to a 33-year -old woman with intractable migraine headaches resistant to standard therapy. Her only abnormality noted was unexplained weight gain. She failed a water load test. Results: The headaches were 100% relieved by dextroamphetamine sulfate (Spansule - 45 mg/day). Conclusions: Intractable migraine headaches can be added to the list of various pain syndromes related to a disorder of the sympathetic nervous system resistant to standard therapy but showing dramatic improvement with treatment with sympathomimetic amines.
Sympathetic nervous system