IMR Press / CEOG / Volume 38 / Issue 2 / pii/1630488784171-432696011

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 46 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Case Report
Evidence that migraine headaches in women may be related to a common defect in the sympathetic nervous system as evidenced by marked improvement following treatment with sympathomimetic amines
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1 The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, Cooper Hospital/University Medical Center, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Inferility, Camden, NJ (USA)
Clin. Exp. Obstet. Gynecol. 2011, 38(2), 180–181;
Published: 10 June 2011
Abstract

Purpose: To describe a novel therapy for women with intractable migraine headaches. Methods: Dextroamphetamine sulfate was prescribed to a 33-year -old woman with intractable migraine headaches resistant to standard therapy. Her only abnormality noted was unexplained weight gain. She failed a water load test. Results: The headaches were 100% relieved by dextroamphetamine sulfate (Spansule - 45 mg/day). Conclusions: Intractable migraine headaches can be added to the list of various pain syndromes related to a disorder of the sympathetic nervous system resistant to standard therapy but showing dramatic improvement with treatment with sympathomimetic amines.
Keywords
Sympathetic nervous system
Sympathomimetic amines
Migraine headaches
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