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Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Original Research
Maternal hemoglobin level and red cell indices as predictors of gestational diabetes in a multi-ethnic Asian population
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1
Department of Obstetrics and Gynecology, University of Malaya, Kuala Lumpur
2
Faculty of Medicine, University of Malaya, Kuala Lumpur
3
Hospital Raja Permaisuri Bainun, Jalan Hospital, Perak (Malaysia)
Clin. Exp. Obstet. Gynecol. 2011, 38(2), 150–154;
Published: 10 June 2011
Abstract
Objective: To evaluate maternal hemoglobin levels and red cell indices as predictive factors for gestational diabetes (GDM). Method: Data from 1 ,538 women were analyzed. At the first visit for prenatal care, the 50-gram glucose challenge test was followed by the 75-gram glucose tolerance test in those who screened positive. GDM was diagnosed based on the WHO (1999) criteria. Maternal complete blood count was obtained at the first visit, hospitalization for birth, and after birth. Receiver operator characteristic curves were generated to establish thresholds. Multivariable logistic regression analyses were performed to establish independent predictors of GDM. Results: GDM was diagnosed in 182/1,538 (11.8%). GDM was associated with hemoglobin level, hematocrit and erythrocyte count at the first visit for prenatal care only. Hemoglobin threshold at the first visit was established at 11.5 g/dl. After adjustment, high hemoglobin [AOR 1.5 (95% CI 1.0-2.1); p = 0.027] remained predictive of GDM. Conclusions: High maternal hemoglobin level at the first prenatal visit is independently predictive of GDM.
Keywords
Hemoglobin
Gestational diabetes
Predictor
Hematocrit
Erythrocyte count