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Case Report
D-dimer levels as a predicting factor for DIC following single twin death: a case report and review of the literature
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1
Department of Pharmacology, Medical School, Aristotle University
2
1st Neonatology Clinic, Hippokratio University Hospital, Thessaloniki (Greece)
Clin. Exp. Obstet. Gynecol. 2010, 37(1), 67–68;
Published: 10 March 2010
Abstract
Background: Intrauterine death of one twin in the second or third trimester occurs in about 1% of all twin pregnancies. The retention in utero of the dead fetus may be associated with maternal disseminated intravascular coagulation. Case: We present the case of a diamniotic monochorionic pregnancy with intrauterine death of the first twin at 24 weeks. The pregnancy reached 33 weeks. In our case although all coagulation factors were within normal limits, D-dimer levels were significantly high, without any evidence though of any clotting problems to the mother. Conclusion: The role of D-dimers is practically unknown in multiple pregnancies. It seems that the interpretation of elevated D-dimer levels is still of limited value for prediction or prognosis of thromboembolic complications of multiple pregnancies.
Keywords
D-dimers
Twin pregnancy
DIC
Intrauterine death