IMR Press / CEOG / Volume 36 / Issue 4 / pii/1630635899338-576951163

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 46 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Original Research
Intramuscular fetal corticosteroid therapy short-term effect on maternal-fetal Doppler velocimetry
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1 Institute for Gynecology and Obstetrics, Clinical Center of Serbia, Belgrade
2 Faculty of Organizational Sciences, University of Belgrade, Institute for Statistics, Belgrade (Serbia)
Clin. Exp. Obstet. Gynecol. 2009, 36(4), 248–250;
Published: 10 December 2009

Aim: The aim of the study was to assess the short-term effects of intramuscular (IM) corticosteroid therapy (CST) on fetoplacental and fetal circulation in high-risk pregnancies of preterm labor. Method: We evaluated the effect of IM fetal single-dose dexamethasone (4 mg/kg) on fetoplacental and fetal circulation two hours before and 0-4 hours after CST in 38 fetuses after the 32nd week of gestation. Result: Changes in the umbilical artery (UA) resistance index (RI) after fetal CST (AU RI1) were significantly correlated with gestational age after the 32nd week at recording r = 0.354; p < 0.05. There was a statistically significant difference of RI in the descending aorta (DAo) before and after therapy; p < 0.001 (-0.04-0.01), 95% confidence interval (CI) for differences. Conclusion: Short-time effects after fetal IM CST include an increased index resistance in DAO as well as decreased RI in UA after the 32nd week.
Fetal corticosteroid therapy
Fetal arterial velocimetry
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