Announcements
Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Original Research
Intramuscular fetal corticosteroid therapy short-term effect on maternal-fetal Doppler velocimetry
I. Babović Babović1,*, S. Plesinac1, J. Opalić Opalić1, I. Pilić Pilić1, Z. Radojicˇić Radojicˇić2, M. Pervulov1, N. Radunović Radunović1, A. Ljubić Ljubić1
Show Less
1
Institute for Gynecology and Obstetrics, Clinical Center of Serbia, Belgrade
2
Faculty of Organizational Sciences, University of Belgrade, Institute for Statistics, Belgrade (Serbia)
Clin. Exp. Obstet. Gynecol. 2009, 36(4), 248–250;
Published: 10 December 2009
Abstract
Aim: The aim of the study was to assess the short-term effects of intramuscular (IM) corticosteroid therapy (CST) on fetoplacental and fetal circulation in high-risk pregnancies of preterm labor. Method: We evaluated the effect of IM fetal single-dose dexamethasone (4 mg/kg) on fetoplacental and fetal circulation two hours before and 0-4 hours after CST in 38 fetuses after the 32nd week of gestation. Result: Changes in the umbilical artery (UA) resistance index (RI) after fetal CST (AU RI1) were significantly correlated with gestational age after the 32nd week at recording r = 0.354; p < 0.05. There was a statistically significant difference of RI in the descending aorta (DAo) before and after therapy; p < 0.001 (-0.04-0.01), 95% confidence interval (CI) for differences. Conclusion: Short-time effects after fetal IM CST include an increased index resistance in DAO as well as decreased RI in UA after the 32nd week.
Keywords
Fetal corticosteroid therapy
Fetoplacental
Fetal arterial velocimetry