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Effect of the degree of fragmentation on embryo survival after freeze-thawing
1 The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, Cooper Hospital/University Medical Center, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, NJ (USA)
Clin. Exp. Obstet. Gynecol. 2009, 36(4), 216–216;
Published: 10 December 2009
Purpose: To determine if the degree of fragmentation of embryos prior to freezing correlate in a negative manner with survival after thawing. Methods: A retrospective review of frozen embryos thawed for purposes of embryo transfer was done. Survival and transferability rates were determined according to degree of fragmentation. Results: The chance that an embryo with <25% fragmentation was deemed good enough for transfer upon thawing was 63.6% compared to 52.8% for embryos >25% (p < .05). Conclusions: Though more fragmented embryos have a lower survival rate after freeze thawing, about 50% of embryos with >25% fragmentation will still survive the thaw and be able to be transferred.