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Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Original Research
An objectıve method to determıne corneal changes durıng menopause
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1
Department of Obstetrics and Gynecology
2
Department of Opthalmology, Istanbul University Faculty of Medicine;
3
Department of Opthalmology, Hospital of Dumlupınar University, Kutahya (Turkey)
Clin. Exp. Obstet. Gynecol. 2009, 36(3), 176–178;
Published: 10 September 2009
Abstract
Objective: We hypothesized that menopause has a measurable effect on corneal thickness. The aim of this study was to evaluate central corneal thickness (CCT) differences between women in the premenopausal and postmenopausal period. Methods: A prospective, case-control, single-blind study was designed. Two groups were included: Group I (premenopausal period) and Group II (postmenopausal period). Forty women were recruited in each group. The correlation between CCT with age, estradiol (E2) and follicle stimulating hormone (FSH) levels were evaluated. Results: CCT was significantly decreased in postmenopausal women compared to premenopausal women (521.18 ± 37.97 μm 561 ± 42.84 μm, respectively, p < 0.005). Similarly, there was a linear correlation between CCT and serum E2 levels of patients overall (p < 0.01). Conclusion: The data presented in this study suggest that menopause causes corneal changes, which may be documented by central corneal thickness measurement.
Keywords
Cornea
Eye
Menopause
Estradiol