IMR Press / CEOG / Volume 36 / Issue 2 / pii/1630635625416-1675331533

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Original Research
Factors affecting bone mineral density of young women and predictive factors of low bone mineral density
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1 School of Health and Nursing Science, Wakayama Medical University
2 Department of Obstetrics and Gynecology, School of Medicine, Wakayama Medical University, Wakayama (Japan)
Clin. Exp. Obstet. Gynecol. 2009, 36(2), 87–90;
Published: 10 June 2009
Abstract

Purpose of investigation: We investigated various factors affecting bone mineral density (BMD) in young women and predictive factors of low BMD. Methods: Subjects were 105 nursing school students aged from 19 to 24 years old. Body weight (BW), pituitary hormones, sex steroid hormone and bone turnover markers were selected as factors. BMD was measured at the lumbar spine at L2-L4 by dual-energy X-ray absorptiometry (DXA). Results: BW (p = 0.002), serum N-terminal telopeptide of type 1 collagen (NTx) (p = 0.006) and bone specific alkaline phosphatase (BAP) (p = 0.02) were significantly correlated with BMD. For identification of the low BMD group, all subjects were divided into four groups on the basis of BW and NTx concentrations. In the group with BW under 51 kg and Ntx concentrations over 11 nMBCE/l, BMD was significantly (p = 0.0013) decreased compared with the other three groups. In this group, the ratio of women with a low BMD was significantly higher (p = 0.004) than the other groups. Conclusion: In young women, BW and bone turnover markers significantly affected BMD. Low BMD can be indicated using BW and NTx concentrations without measurement by DXA.
Keywords
Young women
Osteoporosis
Bone mineral density
Body weight
Serum N-terminal telopeptide of type 1 collagen
Predictive factor
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