IMR Press / CEOG / Volume 35 / Issue 3 / pii/1630638723628-92380149

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Case Report
A case with diffuse uterine leiomyomatosis and review of the literature
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1 Department of Obstetrics and Gynecology Kahramanmaras Sutcu Imam University Medical Faculty
2 Department of Obstetrics and Gynecology, Cukurova University Medical Faculty, Kahramanmaras
3 Department of Pathology, Cukurova University Medical Faculty, Kahramanmaras (Turkey)
Clin. Exp. Obstet. Gynecol. 2008, 35(3), 227–230;
Published: 10 September 2008
Abstract

Leiomyomas and diffuse uterine leiomyomatosis are smooth muscle tumors of the uterus. Diffuse uterine leiomyomatosis is a benign and extremely rare condition in which the uterus is symmetrically enlarged as a result of the almost complete replacement of the myometrium by innumerable poorly defined, confluent nodules. The etiology of these neoplasms is not completely understood. Initial symptoms of the diffuse uterine leiomyomatosis usually are abdominal pain and abnormal uterine bleeding. Similar to uterine leiomyomas, patients with leiomyomatosis present with menorrhagia, dysmenorrhea, abdominal pain, infertility, and pelvic pressure. Hormonal treatment usually fails to control the symptoms, anemia, or tumor growth after treatment is stopped. As a result, despite patients being in the third or fourth decades of life, hysterectomy has been the only permanent treatment option offered to patients for treatment of the symptoms related to uterine fibroids in diffuse leiomyomatosis. A case of a patient with a huge uterine mass (2,650 g in weight) who underwent hysterectomy due to diffuse uterine leiomyomatosis is presented together with a review of the literature.
Keywords
Diffuse uterine leiomyomatosus
Leiomyoma
Management
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