IMR Press / CEOG / Volume 35 / Issue 3 / pii/1630638712242-1515794020

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Original Research
Maternal serum mannose-binding lectin in severe preeclampsia
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1 Department of Obstetrics and Gynecology, Uludag University Medical Faculty, Bursa (Turkey)
Clin. Exp. Obstet. Gynecol. 2008, 35(3), 179–182;
Published: 10 September 2008
Abstract

Purpose: We aimed to investigate the level of serum mannose-binding lectin (MBL) in severe preeclamptic patients, women with uncomplicated pregnancies, and healthy reproductive-age females and its impact on gestational age at delivery and birth weight. Methods: Serum MBL levels were measured in 27 severe preeclampsia patients (Group 1), 27 patients with uncomplicated pregnancies (Group 2), and 25 healthy reproductive-age women (Group 3). Results: The mean serum MBL was significantly higher (p ≤ 0.05) in Group 1 than in Groups 2 and 3, while the levels in Groups 2 and 3 did not significantly differ. The mean gestational age at delivery and mean birth weight were significantly lower in Group 1. In Group 1, serum MBL was negatively correlated (p ≤ 0.05) with the gestational age at delivery and birth weight. Conclusion: Serum MBL increased in preeclampsia and was negatively correlated with the gestational age at birth and birth weight, indicating an underlying immunopathogenesis.
Keywords
Mannose-binding lectin
Preeclampsia
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