IMR Press / CEOG / Volume 35 / Issue 2 / pii/1630638482481-1152380542

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 46 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Review
Placenta percreta presenting in the first trimester: Review of the literature
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1 Department of Obstetrics & Gynaecology, Venizelion General Hospital, Leoforos Knossou, Heraklion Crete
2 Department of General Surgery Venizelion General Hospital, Leoforos Knossou, Heraklion Crete (Greece)
Clin. Exp. Obstet. Gynecol. 2008, 35(2), 98–102;
Published: 10 June 2008

Placenta percreta complicating pregnancy in the first trimester is extremely rare, and only a few cases have been reported in the literature. We recently reported on a patient with risk factors for placenta percreta that presented as first trimester fetal demise, unresponsive to medical management with prostaglandin. The patient required an emergency hysterectomy to control the bleeding after uterine curettage, and was complicated by severe consumption coagulopathy. This rare entity can lead to significant mortality and morbidity, particularly in the background of increased prevalence of the disease and its associated risk factors, and the large number of spontaneous and induced abortions performed worldwide. Therefore, we also reviewed all reported cases of first-trimester placenta percreta in the literature to increase the awareness of physicians and to highlight the clinical features and essentials of the management.
Placenta accreta
First trimester
Early pregnancy
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