Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Regression rate of clinical HPV infection of the lower genital tract during pregnancy after laser CO2 surgery
The objective of the study was to evaluate the effects of laser CO2 surgery during pregnancy to prevent clinical HPV infection recurrence after delivery and vertical infection. A case-control study was performed on 280 pregnant women affected by clinical HPV infection treated during pregnancy with 256 women treated three months after delivery. Follow-up was performed for a minimum of three colposcopic examinations for two years. Recurrence rates were calculated considering the number of positive findings for at least one colposcopic examination confirmed by biopsy after a negative control in a year. Statistical comparison of rates was performed by χ2 and Fisher’s exact test. Recurrence rates were higher in the women treated in postpartum (p < 0.01) than in the group treated during gestation (p < 0.005)
Clinical HPV infections treated during the second trimester of pregnancy showed a sensitive decrease in recurrence rate of infection. Rarity of respiratory papillomatosis makes conclusions inconsistent for the prevention of vertical infection.