Purpose: To determine the efficacy of using embryos cryopreserved more than ten years in a donor embryo program. Methods: Embryos were cryopreserved using a simplified freezing protocol and then donated for anonymous use after the donor had had a successful pregnancy and was sure she did not want to conceive again. Results: Two women in the donor embryo program transferred embryos that had been cryopreserved longer than ten years. Both patients delivered healthy babies. Conclusions: Embryos cryopreserved over ten years can result in successful pregnancies.