IMR Press / CEOG / Volume 32 / Issue 4 / pii/2005074

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Case Report

A pregnant woman with anti-Gregory antigen: case report

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1 Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, Kobe (Japan)
Clin. Exp. Obstet. Gynecol. 2005, 32(4), 257–258;
Published: 10 December 2005
Abstract

Negative Gregory antigen (Gy(a-)) remains an extremely uncommon blood phenotype. We describe a 32-year-old pregnant woman with (Gy(a-)) and anti-Gregory antigen (anti-Gya). There was no evidence of consanguineous mating in her family. Blood typing study revealed that only her father was Gy(a-) among the family. Anti-Gya had a titer of 16 before pregnancy, but increased to 1,024 at 33 weeks of gestation with a titer of 512 at 34 weeks. Her own blood stores were collected starting at 14 weeks, amounting to 1,800 g totally. She underwent an emergency cesarean section at 35 weeks due to a non-reassuring fetal status. Blood loss was approximately 1,090 g. Cord blood type was found to be Gy(a-). The indirect Coombs test of cord blood was postive, while the direct Coombs test was negative. No neonatal hemorrhagic disease developed. The storage of a sufficient amount of crossmatch­compatible Gy(a-) blood during pregnancy is important in case of possible need of blood transfusion at delivery for women with anti-Gya

Keywords
Gregory antigen
Hemolytic disease of the newborn
Pregnancy
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