IMR Press / CEOG / Volume 32 / Issue 3 / pii/2005043

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Review

Upper body venous thrombosis associated with ovarian stimulation: Case report and review of the literature

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1 Department of Gynaecological, Obstetrical Sciences and Reproductive Medicine, Messina (Italy)
2 Department of Neurosciences, Psychiatric and Anaesthesiological Sciences, University of Messina, Messina (Italy)
Clin. Exp. Obstet. Gynecol. 2005, 32(3), 149–154;
Published: 10 September 2005
Abstract

Thromboembolic events are a serious complication of assisted conception treatment. Thrombosis may be either arterial or venous but the latter is far more common. This phenomenon is more frequent in the lower limb, but several cases of upper extremity throm­bosis have been described in the literature. Although the aetiology of these thromboembolic disorders is not fully understood, the mechanism is thought to be due to a hypercoagulable state associated with haemostasis and thrombophilia. Predisposing factors seem to be hyperoestrogenism, ovarian hyperstimulation syndrome, a hereditary hypercoagulable state and multifoetal pregnancy We report a case of superior sagittal sinus thrombosis that developed in a patient following successful assisted conception in the absence of evident risk factors. In the current literature, the site of thrombosis, possible predisposing factors, oestrogen levels, number of foetuses, maternal and foetal outcomes, and management of thrombosis were analysed.

Keywords
Cerebral venous thrombosis
Ovulation induction
OHSS
Thrombophilic state
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