Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Successful pregnancy in a 45-year-old woman with elevated day 3 serum follicle stimulating hormone and a short follicular phase
Purpose: To determine if a successful pregnancy is possible in a woman aged 45 with elevated day 3 serum follicle stimulating hormone (FSH), a short follicular phase, and failure to attain a mature follicle before ovulating. Methods: Ethinyl/estradiol (20 µg daily) was given from day 2 of the menstrual cycle until follicular maturation was attained. Progesterone support of 200 mg twice daily progesterone vaginal suppositories were given in the luteal phase. Results: A mature follicle was attained on day 12 with a serum estradiol of 335 pg/mL. Successful pregnancy and delivery were attained. Conclusions: This is the third reported case of a successful pregnancy in a woman ≥45 years old with hypergonadotropism, and the first one reported that was also complicated by a short follicular phase.