IMR Press / CEOG / Volume 32 / Issue 1 / pii/2005022

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 46 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Case Report

Live delivery following transfer of a single frozen-thawed embryo derived from a 42-year-old woman with marked decreased oocyte reserve

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1 The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, Cooper Hospital/University Medical Center, Department cif Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, NJ (USA)
Clin. Exp. Obstet. Gynecol. 2005, 32(1), 75–77;
Published: 10 March 2005

Purpose: To determine if live birth is possible in a woman of older reproductive age and who has markedly decreased oocyte reserve following frozen embryo transfer of an oocyte fertilized by intracytoplasmic sperm injection of testicular sperm. Methods: Ethinyl estradiol followed by ovarian stimulation with gonadotropins was used and a mature follicle was attained. Following oocyte retrieval 34 hours later, intracytoplasmic sperm injection of testicular sperm was performed. The embryo was cryop­reserved. Results: A live delivery of a full-term baby ensued. Following subsequent frozen embryo transfer, the baby was diagnosed with Down's syndrome and subsequently died.

Conclusion: This is the first report of a live delivery following frozen embryo transfer in a woman of advanced reproductive age with marked decreased oocyte reserve.

Ovarian failure
Frozen embryo transfer
Testicular sperm
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