IMR Press / CEOG / Volume 31 / Issue 4 / pii/2004071

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 46 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Original Research

Cytokines and endometriosis

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1 Karol Marcinkowski University School of Medicine, Poznan (USA)
2 Cancer Center and Institute of Oncology, Warsaw (USA)
3 32nd Department and Clinics of Gynaecology, Medical Academy, Lublin (Poland)
4 Clarkson University, Potsdam NY (USA)
Clin. Exp. Obstet. Gynecol. 2004, 31(4), 269–270;
Published: 10 December 2004

Introduction: Abnormal expression of cytokines is considered to be involved in the pathogenesis of endometriosis. Material and Methods: In 63 women with various stages of endometriosis preoperative levels of cytokines, including IL-6, IL-8, BVEGF, b-FGF, of TNF RI and TNF RII were analysed employing ELISA tests (R&D kits). Results: In the sera of endometriosis patients significantly augmented levels of lL-6 and of b-FGF were detected as well as a trend for elevated IL-8 levels. Conclusion: Elevated serum levels of cytokines may show poor con-espondence to the localized pathological process. Endometnosis would find a stricter reflection in cytokine levels in fluids or tissues of the pelvis minor.

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