Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Shared donor oocyte system to determine if top embryos can be derived from oocyte factors or more likely from an oocyte/sperm interaction
Purpose: To determine if top embryos require an unusual, and possibly fortuitous, combination of excellent oocyte quality and sperm, or whether some oocyte property alone leads to the formation of superior quality embryos on day 3. Methods: The embryo quality of donor oocyte recipient cycles was evaluated to find a woman who made I 00% top embryos. After finding such an individual, the quality of the recipient's embryos was also evaluated. The shared donor oocyte recipient cycles were also evaluated for pregnancy outcome. Results: All 15 embryos were graded top. The six embryos transferred to the donor and recipient resulted in two sets of triplets One of the fetuses of the recipient aborted related to trisomy 21. Conclusion: The data indicates that the formation of an extremely high percentage (100%) of top embryos can be related to an oocyte factor. It is extremely unlikely to find two male partners who produce sperm with a unique property that makes superior morphologic embryos implant.