Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Medical management of ectopic pregnancy with extremely high β-HCG levels: A case report
We report the successful treatment of an unruptured ectopic pregnancy in a patient with extremely high β-human choriomc gonadotropin concentrations. A 33-year-old woman, gravida 2, para 0, abortus I, presented to our department due to menstrual delay On transvaginal ultrasonography, she had an unruptured ectopic pregnancy (3.5 × 4.5 cm). Her initial β-HCG concentration was 38,270 mIU/mL. The administration of methotrexate (50 mg/m2) was performed intramuscularly. Serum β-HCG levels decreased >15% between post-therapy days 4 (31,324 mIU/mL) and 7 (13,108 mIU/mL), and did not rise during the subsequent weekly controls. In selected cases with unruptured ectopic pregnancy and extremely high initial β-HCG levels, medical management with a singledose methotrexate regimen may be successful.