IMR Press / CEOG / Volume 31 / Issue 1 / pii/2004007

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Original Research

Implications of the diagnosis of endometriosis on the success of infertility treatment

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1 Human Reproduction Unit, Department of Obstetrics and Gynaecology Hospital de Santa Maria, Lisbon (Portugal)
Clin. Exp. Obstet. Gynecol. 2004, 31(1), 25–30;
Published: 10 March 2004
Abstract

Purpose: Endometriosis is a clinically very heterogeneous disorder and its implications on the resolution of infertility are not clear. Methods: Clinical data of 783 consecutive infertile couples were retrospectively analyzed in three groups: A - with minimal/mild endometriosis; B - with moderate/severe endometriosis; C - without endometriosis. Subgroups of groups A and C with unexplained infertility were also compared. Results: Endometriosis was found in 349 patients (44.6%) - 263 in group A and 86 in group B. Group C comprised 434 patients Overall pregnancy rates were 57.0% for group A, 48.8% for Band 55.8% for C (not statistically different). Of couples in groups A, B, C, respectively, 39.2%, 51.1 % and 39.2% needed IVF (B vs C - p = 0.042; B vs A - p = 0.059). Of couples in group A 45.6% that underwent IVF achieved a pregnancy by this technique; corresponding numbers were 43.2% for group B and 46.5% for C Overall pregnancy rates in couples with unexplained infertility in groups A (n = 116) and C (n = 110) were respectively, 58.6% and 56.4%; IYF was needed in 40.5% and 32.7% of those couples, and the cumulative pregnancy rates resulting from IVF were 40.4% and 47.2% (NS). Conclusion: The diagnosis of endometriosis had no influence on the successful resolution of infertility although moderate/severe endometriosis was related to a greater need for IVF. Couples with unexplained infertility had similar pregnancy rates either in the presence or in the absence of minimal/mild endometriosis.

Keywords
Endometriosis
Infertility outcome
Unexplained infertility
IVF
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