IMR Press / CEOG / Volume 30 / Issue 4 / pii/2003053

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Original Research

Preoperative evaluation of ovarian masses: ultrasound and biochemical screening

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1 Department of Gynaecological Sciences, Perinatology and Puericulture Ⅲ Division of Obstetrics and Gynaecology-Rome University “La Sapienza” (Italy)
Clin. Exp. Obstet. Gynecol. 2003, 30(4), 217–219;
Published: 10 December 2003
Abstract

Objective: The preoperative study of an ovarian mass, with a negative dosage of plasmatic BhCG, mainly has the purpose of dis­criminating between a benign neoplastic mass and a malignant mass. The aim of our work was to evaluate the validity of preoperative screening including a pelvic ultrasound examination and the dosage of some plasmatic tumor markers. Methods: This is a retrospective study conducted on 78 patients who were referred to the III Division of the Department of Gynae­cological Sciences, Perinatology and Puericulture of Rome University “La Sapienza” from January 1st 2001 to December 31st 2001 with a diagnosis of ovarian tumefaction whose origin was still to be determined. These patients underwent both a transabdominal and transvaginal ultrasound scan and biochemical examination of serum levels of Ca-125, Ca 19-9 and CEA. Subsequently these patients underwent surgery or medical therapy according to the suspected diagnosis. We then compared our suspected diagnosis with the precise histological diagnosis. Finally, following this comparison, we judged the validity of the proposed screening. Results: Ultrasound examination is on its own an excellent method for preoperative screening in cases of adnexal tumefactions. However, its association with plasmatic dosages of Ca 125, Ca 19-9 and CEA improves the validity of the screening. Conclusion: The use of pelvic scanning, both transabdominal and transvaginal, associated with plasmatic dosages of Ca 125, Ca 19-9 and CEA, represents an excellent method of preoperative screening for the evaluation of benign or malignant ovarian tume­factions and for directing the surgeon towards the best therapy.

Keywords
Ovarian cancer
Ultrasound
Ca 125
Ca 19-9
CEA
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